Get medical help right away if you develop some of the following symptoms: A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: This is not a complete list of possible side effects.
If you notice other effects not listed above, contact your doctor or pharmacist. In the US -Call your doctor for medical advice about side effects. In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at Before taking duloxetine, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies.
This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details. Before using this medication, tell your doctor or pharmacist your medical history, especially of: This drug may make you dizzy or drowsy.
Do not drive, use machinery, or do any activity that requires alertness until you are sure you can perform such activities safely. If you have diabetes , duloxetine may affect your blood sugar levels.
Check your blood sugar levels regularly as directed by your doctor. Your doctor may need to adjust your diabetes medication, exercise program, or diet. Before having surgery, tell your doctor or dentist about all the products you use including prescription drugs, nonprescription drugs, and herbal products.
Older adults may be more sensitive to the side effects of this drug, especially bleeding, or loss of coordination. Older adults may also be more likely to develop a type of salt imbalance hyponatremia , especially if they are taking "water pills" diuretics.
Loss of coordination can increase the risk of falling. Children may be more sensitive to the side effects of this drug, especially loss of appetite and weight loss. Monitor weight and height in children who are taking this drug. During pregnancy , this medication should be used only when clearly needed. It may harm an unborn baby. If you notice any of these symptoms in your newborn , tell the doctor promptly.
Since untreated depression can be a serious condition, do not stop taking this medication unless directed by your doctor. If you are planning pregnancy, become pregnant, or think you may be pregnant, immediately discuss the benefits and risks of using this medication during pregnancy with your doctor.
This drug passes into breast milk and may have undesirable effects on a nursing infant. Consult your doctor before breast-feeding. Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Do not start, stop, or change the dosage of any medicines without your doctor's approval. Some products that may interact with this drug include: However, there have been no reports of hepatic failure.
Duloxetine is not recommended in patients with end-stage renal disease or severe renal impairment because of the increased plasma concentrations of the drug and its metabolites. Duloxetine is FDA pregnancy category C based on negative animal studies; there have been no trials assessing its use in pregnant women. Tolerability In clinical trials for depression, the discontinuation rate in patients receiving duloxetine was significantly higher than in patients receiving placebo approximately 10 percent and 4 percent, respectively.
Changes in heart rate, blood pressure, and weight are not clinically significant. There are no data comparing duloxetine with other anti-depressants in terms of their impacts on the rates of sexual dysfunction.
Effectiveness Four studies involving a total of 1, patients with major depression have demonstrated the superiority of duloxetine over placebo based on the Hamilton Depression Rating Scale. There are no data regarding the effectiveness of duloxetine for preventing recurrence of symptoms.
Although duloxetine is marketed for the treatment of painful physical symptoms associated with depression, research results do not support its effectiveness for this use. In manufacturer-conducted studies, patients with low baseline pain scores had clinically insignificant changes in pain scores, with no significant improvement in overall pain or functional status. In the treatment of painful diabetic neuropathic pain, studies involving patients showed duloxetine, 60 mg once or twice daily, to be more effective than placebo.
Read More I'm feeling much better now and will have a talk with my MD that prescribed the Cymbalta and tramadol. Thanks for the input! The only downside to the Lyrica was difficulty with cognition and drowsiness. Savella milnacipran is the new medication and it works much the same as Cymbalta As uk2 mentioned, the patches help with pain as well.
It's much a 'trial and error' Read More I was prescribed Topamax along with an appetite suppressant Adipex for weight loss a bit over a year ago and stopped taking them after two and a half months.
I did not lose all of the weight I had wanted to, but most of it. I had gained 55 pounds while on Paxil over the course of two and a half years. By taking a combination of the two medicines, I lost 22 pounds the first month, 10 pounds the second month, and 8 pounds the first half of the third month. Read More More will be coming along in a few hours and their are plenty of people here who have experience with tramadol ,as well as cymbalta and wellbutrin.
Congratulations on getting off the narco and for making the decision to want to live a drug free life,thats great
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