Dosages greater than 20 mg per day may be administered once daily in the morning or twice daily morning and noon if necessary. Maximum daily doses should not exceed 80 mg per day. Prozac has also been proven effective for once weekly administration. For the treatment of major depressive disorder in the pediatric population, 8 years of age and older, the usual recommended Prozac dosage is 10 to 20 mg per day. Treatment with Prozac for major depressive disorder may require four weeks or longer before the full pharmacologic effect is observed.
For the treatment of obsessive-compulsive disorder in adults, the initial Prozac dosage is 20 mg per day administered in the morning. The usual recommended Prozac dosages range from 20 to 60 mg per day. However, 80 mg per day dosages have been well tolerated in clinical studies.
The maximum daily dose is 80 mg. For the treatment of obsessive-compulsive disorder in adolescents and higher weight children, 7 years of age and older, the usual recommended Prozac dosage is 20 to 60 mg per day with an initial dosage of 10 mg per day. For lower weight children, 20 to 30 mg per day is recommended. For the treatment of bulimia nervosa in adults, the usual recommended Prozac dosage is 60 mg per day administered in the morning. In some patients, dose titration over several days may be advisable.
For the treatment of panic disorder in adults, the initial Prozac dosage is 10 mg per day. According to the prescribing information, the dosage should be increased to 20 mg daily after one week of treatment. The usual recommended Prozac dosage is 20 mg per day administered in the morning.
During clinical trials, patients were administered dosages ranging from 10 to 60 mg. A dosage of 20 mg was most frequently administered to patients during clinical trials. For all indications of Prozac, it may require four weeks of treatment or longer before patients experience improvements in symptoms.
It is essential for patients to continue with treatment exactly as directed to achieve desired therapeutic outcomes. What is the difference between generic and brand Prozac? In most patients, there is no significant difference between generic and brand Prozac fluoxetine. There is currently a generic equivalent available for Prozac, known as fluoxetine. Food and Drug Administration FDA requires that generic medications be bioequivalent to the brand-name medication and, therefore, exert the same pharmacologic effects in the body.
Generic medications are considered, by the FDA, to be therapeutically identical to the brand-name counterparts in dose, strength, route of administration, safety, efficacy and indication for use. Generic medications will appear differently and may have different inactive ingredients, however, the labeling and directions for use remain the same.
For most medications, generic equivalents are a lower-cost alternative to the more expensive brand-name medication, and the majority of patients observe no changes in therapeutic effect.
However, some patients may experience a change in therapeutic effect and, subsequently, must continue treatment with the brand-name medication. Generic Prozac, fluoxetine, is a selective serotonin reuptake inhibitor SSRI antidepressant which is approved for the treatment of major depressive disorder, obsessive-compulsive disorder OCD , panic disorder and bulimia nervosa. Frequently reported side effects for generic Prozac are similar those observed in patients being treated with the brand-name medication and may include abnormal dreams, abnormal ejaculation, anorexia, anxiety, asthenia, diarrhea, dry mouth, dyspepsia, flu syndrome, impotence, insomnia, decreased libido, nausea, nervousness, pharyngitis, rash, sinusitis, somnolence, sweating, tremor, vasodilatation and yawn.
The warnings and precautions associated with Prozac are also possible with the generic fluoxetine. According to the prescribing information for Prozac, warnings and precautions, possible with treatment, include clinical worsening of depression and suicide risk, serotonin syndrome or neuroleptic malignant syndrome-like reactions, allergic reactions and rash, activation of mania or hypomania, seizures, altered appetite and weight, abnormal bleeding, hyponatremia, possibility of anxiety and insomnia, potential for cognitive and motor impairment and long half-life affecting changes in dosage.
Fluoxetine, generic Prozac, should be administered exactly the same as the brand-name medication. Fluoxetine is typically taken once daily and administered in the morning. Is Prozac for insomnia? Prozac fluoxetine is not indicated for insomnia treatment by the U.
Prozac is approved by the FDA for the treatment of several other medical conditions including depression, obsessive-compulsive disorder, bulimia nervosa and panic disorder. During clinical trials, one of the most commonly observed adverse reactions in patients being treated with Prozac, for any indication, was insomnia.
Patients should be advised to take Prozac exactly as directed by their health care provider. If patients experience unpleasant or bothersome adverse reactions, such as insomnia, they are also advised not to change their dosing regimen or discontinue treatment without consulting with their health care provider. Prozac fluoxetine is an antidepressant categorized as a selective serotonin reuptake inhibitor SSRI.
Prozac is approved, by the U. Food and Drug Administration FDA for the acute and maintenance treatment of major depressive disorder in adult and pediatric patients aged 8 to 18 years, the acute and maintenance treatment of obsessive-compulsive disorder in adult and pediatric patients aged 7 to 17 years, the acute and maintenance treatment of bulimia nervosa in adult patients and the acute treatment of panic disorder, with or without agoraphobia in adult patients.
Prozac is typically administered in the morning and the recommended dosage depends on indication for use. Prozac is available in a capsule formulation in 10 mg, 20 mg and 40 mg strengths. Prozac is also available in a capsule formulation for weekly administration in 90 mg strength. At least five weeks should be allowed after discontinuation of Prozac treatment prior to initiation of treatment with an MAOI because of the long half-life of Prozac.
Prozac is also contraindicated in patients being treated with pimozide and thioridazine because of dangerous drug interactions. Do not use thioridazine within five weeks of discontinuing Prozac treatment.
There are several warnings and precautions associated with Prozac treatment that patients should discuss in detail with their health care provider and understand fully prior to initiation of treatment.
According to the prescribing information, the warnings and precautions, possible with Prozac treatment, include clinical worsening of depression and suicide risk, serotonin syndrome or neuroleptic malignant syndrome-like reactions, allergic reactions and rash, activation of mania or hypomania, seizures, altered appetite and weight, abnormal bleeding, hyponatremia, possibility of anxiety and insomnia, potential for cognitive and motor impairment and long half-life affecting changes in dosage.
Prozac is extensively metabolized broken down in the liver by the cytochrome P system and, therefore, has the potential to interact with several medications. It is essential for patients to inform their health care provider of all medications they are currently taking, including prescription medications, over the counter products and dietary or herbal supplements.
Treatment with Prozac, for all indications, may require four weeks of treatment or longer before patients experience improvements in symptoms.
What are the benefits and risks of Prozac? There are several benefits and risks of Prozac fluoxetine. For most patients, the benefits outweigh the risks of treatment with Prozac. However, there are still various risks a patient should be aware of prior to initiation of therapy. The benefits of Prozac extend across many medical conditions. Prozac, a selective serotonin reuptake inhibitor SSRI antidepressant, is a proven effective treatment option and has demonstrated benefits in patients with major depressive disorder, obsessive-compulsive disorder, panic disorder and bulimia.
In addition, Prozac has proven benefits for major depressive disorder and obsessive-compulsive disorder in the pediatric population as well. There are no drug treatments that are not without risk, including Prozac. One of the risks of Prozac treatment is the commonly occurring side effects. The most commonly reported side effects in patients treated with Prozac include abnormal dreams, abnormal ejaculation, anorexia, anxiety, asthenia, diarrhea, dry mouth, dyspepsia, flu syndrome, impotence, insomnia, decreased libido, nausea, nervousness, pharyngitis, rash, sinusitis, somnolence, sweating, tremor, vasodilatation and yawn.
Other risks of Prozac include several warnings and precautions which may occur with treatment. There is a risk of clinical worsening of depression symptoms and risk of suicide in both the adult and pediatric population.
Clinical trials revealed that antidepressant drugs increase the risk of suicidality in children, adolescents and young adults ages 18 to 24 with major depressive disorder and other psychiatric disorders.
According to the prescribing information, all patients being treated with antidepressants, including Prozac, for any indication should be closely monitored and observed for clinical worsening, suicidality and unusual changes in behavior, especially during the first few months of therapy or during times of dosage adjustments. Patients should be monitored for the following symptoms, anxiety, agitation, panic attacks, insomnia, irritability, hostility, aggressiveness, impulsivity, akathesia, hypomania and mania.
These symptoms have been reported in adults and the pediatric population being treated with antidepressants for major depressive disorder, in addition to other psychiatric and nonpsychiatric indications.
It is important to advise patients taking Prozac to be aware of the risk for serotonin syndrome or neuroleptic malignant syndrome NMS -like reactions that may occur with SSRIs alone or with the concomitant use of Prozac and other serotonergic medications, such as the triptans medications used to treat migraine headaches , tramadol, serotonin-norepinephrine reuptake inhibitors SNRIs , such as Cymbalta duloxetine , Effexor venlafaxine or Pristiq desvenlafaxine , or other SSRIs. Symptoms of serotonin syndrome or NMS-like reactions include agitation, confusion, increased heart rate and blood pressure, sweating, headache, diarrhea, loss of muscle coordination, and possibly fever and seizures.
Seek immediate medical attention if you experience any of these signs and symptoms. Prozac may cause an increased risk for bleeding.
Patients taking Prozac should discuss the concomitant use of Prozac with non-steroidal anti-inflammatory drugs NSAIDs , including ibuprofen and naproxen, aspirin, warfarin or other medications that affect coagulation with their physician to avoid an increased risk for bleeding. Before taking any of these medications, it is important to consult with your physician and call your physician immediately if you experience any bleeding or bruising.
Hyponatremia low levels of sodium in the blood has been reported as a result of Prozac treatment. It is important to be aware of the signs and symptoms associated with hyponatremia so you can recognize them if they occur.
Signs and symptoms include headache, difficulty concentrating, memory impairment, confusion, weakness, unsteadiness, hallucination, passing out, seizure, coma, respiratory arrest and death. Patients should discuss the benefits and risks of Prozac with their health care provider prior to initiation of treatment. What is the difference between Cymbalta versus Prozac? There are a number of differences between Cymbalta duloxetine versus Prozac fluoxetine. The main differences between Cymbalta versus Prozac include mechanism of action, the way in which the drug works in the body, and indications for use approved by the U.
Cymbalta is a potent inhibitor of both serotonin and norepinephrine reuptake in the central nervous system, while Prozac is a much more potent inhibitor of serotonin reuptake than norepinephrine.
The only common indication between Cymbalta and Prozac is major depressive disorder. Cymbalta belongs to a class of antidepressants known as serotonin norepinephrine reuptake inhibitors SNRI and is indicated for the treatment of major depressive disorder, generalized anxiety disorder, diabetic peripheral neuropathic pain, fibromyalgia and chronic musculoskeletal pain.
Prozac belongs to a different class of antidepressants known as selective serotonin reuptake inhibitors SSRI and is indicated for the treatment of major depressive disorder, obsessive-compulsive disorder, panic disorder and bulimia nervosa. Another difference between Cymbalta versus Prozac is approved use in the pediatric population. While Prozac is currently approved, by the FDA, for the treatment of major depressive disorder and obsessive-compulsive disorder in the pediatric population, both in children and adolescents, the safety and effectiveness of Cymbalta in the pediatric population has not been established.
Another difference between Cymbalta versus Prozac is there is currently no generic equivalent available for Cymbalta, while Prozac is available in a generic form, known as fluoxetine.
Cymbalta and Prozac have similar adverse reactions and warnings and precautions associated with treatment. However, Cymbalta has been associated with an increased risk of mydriasis prolonged dilation of the pupils of the eye and should be used cautiously in patients with controlled narrow-angle glaucoma. Patients should be advised to discuss with their health care provider if they have a past medical history of glaucoma prior to initiation of treatment with Cymbalta.
Another difference between Cymbalta versus Prozac, with regard to warnings and precautions, Cymbalta treatment was observed to worsen glycemic control in some patients with diabetes during clinical trials. How do I take Prozac for depression? To take Prozac fluoxetine for depression, patients should be advised that treatment may require four weeks or longer before the full therapeutic effect of Prozac is observed.
It is essential for patients to take Prozac for depression exactly as prescribed by a health care provider and not to adjust the dosing regimen or discontinue treatment with Prozac without the supervision of their doctor.
Prozac is indicated for the treatment of depression in adult and pediatric patients, aged 8 to 18 years. To take Prozac for depression, the initial adult dose is 20 mg per day administered in the morning. The usual dosage of Prozac for depression ranges from 20 to 80 mg daily. During clinical trials for depression, 20 mg daily was an adequate dosage, in most patients, to achieve a desired therapeutic outcome. Research suggests that dosages higher than 20 mg per day may be administered once daily in the morning or may be administered twice daily when necessary, in the morning and at noon.
To take Prozac for depression, the maximum daily dose is 80 mg. Prozac for weekly administration is also effective for treating depression in adults.
To take Prozac for depression in children and adolescents, age 8 and older, the usual dose of Prozac is 10 to 20 mg daily. For both adult and pediatric patients, an increase in dosage of Prozac may be considered after several weeks of treatment if a less than satisfactory clinical improvement is observed. It is essential that patients are periodically monitored and reassessed to determine if further treatment is required.
When taking Prozac for depression, doses are typically administered in the morning unless otherwise instructed. Patients taking Prozac for depression should be informed regarding the most commonly observed adverse reactions. Prior to beginning treatment with Prozac for depression, it is essential to inform your physician of any other medications you are currently taking, including prescription medications, over the counter products and dietary or herbal supplements to avoid potentially dangerous interactions.
How can I lose weight after Prozac? In placebo-controlled clinical trials for major depressive disorder, obsessive-compulsive disorder and bulimia nervosa, altered appetite and weight after beginning Prozac treatment was reported. Patients did not report weight gain or difficulty losing weight during clinical studies or postmarketing experience with Prozac.
Prozac is a potent inhibitor of neuronal serotonin reuptake in the central nervous system and therefore categorized as a selective serotonin reuptake inhibitor SSRI. Prozac is used for the treatment of bulimia, panic disorder, obsessive-compulsive disorder and major depressive disorder. The tools with which to lose weight after Prozac are the same as those for any other individual attempting to lose weight.
In general, irrespective of drug therapy, the safest and most effective method for long-term weight loss is proper diet and exercise. Eating a healthy, well-balanced diet full of fruits, vegetables and whole grains while limiting sugar, processed foods and alcohol typically people lose weight. According to the National Heart Lung and Blood Institute NHLBI , a part of the National Institutes of Health NIH , to lose weight it is essential for individuals to make lifestyle changes which focus on reducing calories from food and drink, a healthy eating plan and proper portion control.
Furthermore, the NHLBI outlines a healthy eating plan to control portion sizes and include fruits, vegetables, whole grains and fat-free or low-fat dairy products. A healthy eating plan should also include lean meats, poultry, fish, beans, eggs and nuts and be low in saturated fat, trans fat, cholesterol, sodium and added sugars. To safely and effectively lose weight, in general and after Prozac, individuals need to expend more calories than they take in.
Essentially, individuals need to reduce their daily caloric intake from food and beverages and increase calories burned through physical exercise. An appropriate diet and exercise regimen should initially be under the guidance of a physician. How can I treat bipolar disorder with Prozac? To treat bipolar disorder with Prozac fluoxetine , another medication must be prescribed in combination.
Prozac is not currently approved as monotherapy for the treatment of depressive episodes associated with bipolar disorder. Symbyax is approved by the U. Food and Drug Administration FDA for the acute treatment of depressive episodes associated with bipolar disorder in adults. To treat bipolar disorder with Prozac in combination with olanzapine most physicians will prescribe combination Symbyax. The efficacy of Symbyax for the acute treatment of depressive episodes associated with bipolar disorder was established in controlled studies.
Symbyax should be administered once daily in the evening. While both Prozac and olanzapine individually can be administered without regard to meals, the effect of food on Symbyax specifically has not been evaluated. According to the prescribing information for Symbyax, dosage changes should be assessed according to efficacy and patient tolerability. The ideal duration of treatment with Symbyax is unknown and patients should be periodically reassessed by a health care provider to determine if continued treatment is necessary.
Patients should be advised to avoid alcohol while being treated with Symbyax. To treat bipolar disorder with Symbyax, it is important for patients to take this medication exactly as prescribed even after mood symptoms improve. Patients should also be advised not to adjust their dosing regimen or discontinue treatment with Symbyax without the supervision of their health care provider.
What condition is Prozac used for? Is it used in weight reduction? Crushing the tablet and making sure the shell fragments are evenly distributed in the powder would be a more precise way of tapering than cutting up tablets.
As Pristiq's extended-release mechanism is part of the tablet matrix, or the glue that holds the tablet together, when the tablet is crushed, the matrix is completely destroyed. The Pristiq powder becomes desvenlafaxine, with an hour half life. If you pulverize the tablet, you might take smaller divided doses of Pristiq, more than once a day, like immediate-release Effexor , to mimic an extended-release dose. Peer discussion of this method starts here http: Before trying a switch to Effexor or Prozac fluoxetine from mg Pristiq, it's probably wise to go down to 50mg Pristiq first, if possible.
Once at 50mg, stabilize for a month at least and consider your plan for the next stage of tapering. Use a combination of Pristiq tablets and Effexor liquid Pristiq cannot be made into a liquid, but its close relative immediate-release Effexor not Effexor XR can. You may be able to go off Pristiq by taking part of your dose in lower-dose tablets and part in liquid Effexor, gradually converting to all-liquid Effexor as you get to lower dosages.
This may offer a convenient and gradual path off Pristiq. Only regular immediate-release Effexor can be made into a liquid see Tips for tapering off Effexor venlafaxine. As immediate-release Effexor has a short half-life and is usually dosed twice a day, you may wish to take the liquid portion of your dosage later in the day.
For example, if you are taking mg Pristiq, you may wish to take your daily dose as one 50mg tablet and the rest in a liquid made from immediate-release Effexor. Then you can take a 25mg Pristiq tablet with the rest in a liquid made from immediate-release Effexor. When you get to 25mg Pristiq, you might switch to splitting the tablet and taking the rest in Effexor liquid and so on until you are taking only liquid Effexor.
You will have to request a prescription for Effexor tablets as well as Pristiq from your doctor. Have Pristiq made into smaller dosage capsules by a compounding pharmacy Compounding pharmacies can crush the tablets and put the powder into smaller capsules by weight.
Like cutting up tablets or crushing, this destroys the time-release quality, but the compounded method is much more exact. According to my compounding pharmacy, they can put in a slow-release additive distributing absorption over hours. This is not as long as the Pristiq time-release coating, but at least it's something.
Check with your compounding pharmacy about this. In your body, crushed Pristiq is similar to regular immediate-release Effexor, with an hour half-life. The MoA of the company contains power to amalgamate. If not, alter the object clause of memorandum by following the procedure laid down under section The Draft scheme of amalgamation based on fair exchange ratio prepared and approved by the Board of Directors. It is always preferred to have the valuation of shares by an outside expert to determine the fair exchange value of shares.
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Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed. Every effort has been made to ensure that the information provided by Cerner Multum, Inc. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise.
Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient.
In subjects with renal impairment the clearance of Pristiq was decreased. The recommended dose in patients with moderate to severe hepatic impairment is 50 mg per day. Dose escalation above mg per day is not recommended [see Clinical Pharmacology Drug Abuse and Dependence Pristiq is not a controlled substance.
Overdosage Human Experience with Overdosage There is limited clinical trial experience with desvenlafaxine succinate overdosage in humans. However, desvenlafaxine Pristiq is the major active metabolite of venlafaxine. Overdose experience reported with venlafaxine the parent drug of Pristiq is presented below; the identical information can be found in the Overdosage section of the venlafaxine package insert.
The most commonly reported events in overdosage include tachycardia, changes in level of consciousness ranging from somnolence to coma , mydriasis, seizures, and vomiting. Published retrospective studies report that venlafaxine overdosage may be associated with an increased risk of fatal outcomes compared to that observed with SSRI antidepressant products, but lower than that for tricyclic antidepressants.
Epidemiological studies have shown that venlafaxine-treated patients have a higher pre-existing burden of suicide risk factors than SSRI-treated patients. The extent to which the finding of an increased risk of fatal outcomes can be attributed to the toxicity of venlafaxine in overdosage, as opposed to some characteristic s of venlafaxine-treated patients, is not clear.
Management of Overdosage No specific antidotes for Pristiq are known. In managing over dosage, consider the possibility of multiple drug involvement.
In case of overdose, call Poison Control Center at for latest recommendations. Pristiq Description Pristiq is an extended-release tablet for oral administration that contains desvenlafaxine succinate, a structurally novel SNRI for the treatment of MDD.
Desvenlafaxine O-desmethylvenlafaxine is the major active metabolite of the antidepressant venlafaxine, a medication used to treat major depressive disorder. Desvenlafaxine succinate monohydrate has a molecular weight of The structural formula is shown below. Desvenlafaxine succinate is a white to off-white powder that is soluble in water.
The solubility of desvenlafaxine succinate is pH dependent.
You may want to discuss using Gas-X simethicone to help treat your symptoms, as it makes the gas bubble break same into many samer sizes, which are easy to pass. I felt fine after that. The last time I took an anti-depressant Prozac was when I was first diagnosed in 8th grade. No adjustment of dosage on the basis of race is prozac. Prozac fluoxetine is a medication that is used to treat depression, pristiq same prozac, anxiety or panic disorders. Pristiq with pristiq is extremely patient-specific. Prozac should not be taken on an as needed basis. According to this paperpristiq same prozac, the extended-release formulation releases desvenlafaxine over 24 hours. In answer to your pristiq about comparing the doses of venlafaxine to desvenlafaxine, there are three articles attached, published in the journal Crestor buy canada edit, CNS Spectrums which may be of use to you. Larger fragments are more likely to retain some extended-release capability. For most medications, generic equivalents are a lower-cost alternative to the more expensive brand-name medication, and the majority of patients observe no changes prozac same effect. Then you can take a 25mg Pristiq tablet with the rest in prozac same prozac from immediate-release Effexor, pristiq same prozac. The warnings and precautions pristiq with Prozac are also possible with the generic fluoxetine.
The tools with which to pristiq weight after Prozac are the same as pristiq for any other individual attempting to lose weight, pristiq same prozac. As always, talk with your health care provider regarding questions you have about your prozac and associated side effects. Consult your healthcare provider about any unusual weight gain and prozac see if changing medications is appropriate based on your specific circumstances. See Same an diclofenac sodium 75mg breastfeeding syringe and other tapering techniques Refrigerate homemade liquids Most homemade solutions may keep for at least a few days, refrigerated, pristiq same prozac. Measure your dose and take it With a liquid, you use an oral syringe to take the dosage you wish. Consult your doctor for same details. It is only by thoughtful suggestions like yours, and colleagues pristiq take the time to email me, that I am able to incorporate the best possible information. Sarah Lewis, PharmD Q: Lisa Lorden Myers Prozac 6, at 9:
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